Radeon Instinct MI250X vs Quadro 4000

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Primary details

GPU architecture, market segment, value for money and other general parameters compared.

Place in the ranking702not rated
Place by popularitynot in top-100not in top-100
Cost-effectiveness evaluation0.16no data
Power efficiency1.87no data
ArchitectureFermi (2010−2014)CDNA 2.0 (2021)
GPU code nameGF100Aldebaran
Market segmentWorkstationWorkstation
Release date2 November 2010 (14 years ago)8 November 2021 (3 years ago)
Launch price (MSRP)$1,199 no data

Cost-effectiveness evaluation

Performance to price ratio. The higher, the better.

no data

Detailed specifications

General parameters such as number of shaders, GPU core base clock and boost clock speeds, manufacturing process, texturing and calculation speed. Note that power consumption of some graphics cards can well exceed their nominal TDP, especially when overclocked.

Pipelines / CUDA cores25614080
Core clock speed475 MHz1000 MHz
Boost clock speedno data1700 MHz
Number of transistors3,100 million58,200 million
Manufacturing process technology40 nm6 nm
Power consumption (TDP)142 Watt500 Watt
Texture fill rate15.201,496
Floating-point processing power0.4864 TFLOPS47.87 TFLOPS
ROPs32no data
TMUs32880

Form factor & compatibility

Information on compatibility with other computer components. Useful when choosing a future computer configuration or upgrading an existing one. For desktop graphics cards it's interface and bus (motherboard compatibility), additional power connectors (power supply compatibility).

InterfacePCIe 2.0 x16PCIe 4.0 x16
Length241 mm267 mm
Width1-slot2-slot
Supplementary power connectors1x 6-pin2x 8-pin

VRAM capacity and type

Parameters of VRAM installed: its type, size, bus, clock and resulting bandwidth. Integrated GPUs have no dedicated video RAM and use a shared part of system RAM.

Memory typeGDDR5HBM2e
Maximum RAM amount2 GB128 GB
Memory bus width256 Bit8192 Bit
Memory clock speed702 MHz1600 MHz
Memory bandwidth89.86 GB/s3,277 GB/s

Connectivity and outputs

Types and number of video connectors present on the reviewed GPUs. As a rule, data in this section is precise only for desktop reference ones (so-called Founders Edition for NVIDIA chips). OEM manufacturers may change the number and type of output ports, while for notebook cards availability of certain video outputs ports depends on the laptop model rather than on the card itself.

Display Connectors1x DVI, 2x DisplayPortNo outputs

API compatibility

List of supported 3D and general-purpose computing APIs, including their specific versions.

DirectX12 (11_0)N/A
Shader Model5.1N/A
OpenGL4.6N/A
OpenCL1.13.0
VulkanN/AN/A
CUDA2.0-

Pros & cons summary


Recency 2 November 2010 8 November 2021
Maximum RAM amount 2 GB 128 GB
Chip lithography 40 nm 6 nm
Power consumption (TDP) 142 Watt 500 Watt

Quadro 4000 has 252.1% lower power consumption.

Instinct MI250X, on the other hand, has an age advantage of 11 years, a 6300% higher maximum VRAM amount, and a 566.7% more advanced lithography process.

We couldn't decide between Quadro 4000 and Radeon Instinct MI250X. We've got no test results to judge.


Should you still have questions concerning choice between the reviewed GPUs, ask them in Comments section, and we shall answer.

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NVIDIA Quadro 4000
Quadro 4000
AMD Radeon Instinct MI250X
Radeon Instinct MI250X

Comparisons with similar GPUs

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Community ratings

Here you can see the user ratings of the compared graphics cards, as well as rate them yourself.


3.6 181 vote

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3.5 123 votes

Rate Radeon Instinct MI250X on a scale of 1 to 5:

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Questions & comments

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