Radeon Instinct MI250 vs Quadro RTX A6000

Primary details

GPU architecture, market segment, value for money and other general parameters compared.

Place in the ranking37not rated
Place by popularitynot in top-100not in top-100
Cost-effectiveness evaluation10.30no data
Power efficiency13.52no data
ArchitectureAmpere (2020−2024)CDNA 2.0 (2021)
GPU code nameGA102Aldebaran
Market segmentWorkstationWorkstation
Release date5 October 2020 (4 years ago)8 November 2021 (3 years ago)
Launch price (MSRP)$4,649 no data

Cost-effectiveness evaluation

Performance to price ratio. The higher, the better.

no data

Detailed specifications

General parameters such as number of shaders, GPU core base clock and boost clock speeds, manufacturing process, texturing and calculation speed. Note that power consumption of some graphics cards can well exceed their nominal TDP, especially when overclocked.

Pipelines / CUDA cores1075213312
Core clock speed1410 MHz1000 MHz
Boost clock speed1800 MHz1700 MHz
Number of transistors28,300 million58,200 million
Manufacturing process technology8 nm6 nm
Power consumption (TDP)300 Watt500 Watt
Texture fill rate604.81,414
Floating-point processing power38.71 TFLOPS45.26 TFLOPS
ROPs112no data
TMUs336832
Tensor Cores336no data
Ray Tracing Cores84no data

Form factor & compatibility

Information on compatibility with other computer components. Useful when choosing a future computer configuration or upgrading an existing one. For desktop graphics cards it's interface and bus (motherboard compatibility), additional power connectors (power supply compatibility).

InterfacePCIe 4.0 x16PCIe 4.0 x16
Length267 mm267 mm
Width2-slot2-slot
Supplementary power connectors8-pin EPS2x 8-pin

VRAM capacity and type

Parameters of VRAM installed: its type, size, bus, clock and resulting bandwidth. Integrated GPUs have no dedicated video RAM and use a shared part of system RAM.

Memory typeGDDR6HBM2e
Maximum RAM amount48 GB128 GB
Memory bus width384 Bit8192 Bit
Memory clock speed2000 MHz1600 MHz
Memory bandwidth768.0 GB/s3,277 GB/s
Shared memory--

Connectivity and outputs

Types and number of video connectors present on the reviewed GPUs. As a rule, data in this section is precise only for desktop reference ones (so-called Founders Edition for NVIDIA chips). OEM manufacturers may change the number and type of output ports, while for notebook cards availability of certain video outputs ports depends on the laptop model rather than on the card itself.

Display Connectors4x DisplayPort 1.4aNo outputs

API compatibility

List of supported 3D and general-purpose computing APIs, including their specific versions.

DirectX12 Ultimate (12_2)N/A
Shader Model6.7N/A
OpenGL4.6N/A
OpenCL3.03.0
Vulkan1.3N/A
CUDA8.6-

Pros & cons summary


Recency 5 October 2020 8 November 2021
Maximum RAM amount 48 GB 128 GB
Chip lithography 8 nm 6 nm
Power consumption (TDP) 300 Watt 500 Watt

RTX A6000 has 66.7% lower power consumption.

Instinct MI250, on the other hand, has an age advantage of 1 year, a 166.7% higher maximum VRAM amount, and a 33.3% more advanced lithography process.

We couldn't decide between Quadro RTX A6000 and Radeon Instinct MI250. We've got no test results to judge.


Should you still have questions concerning choice between the reviewed GPUs, ask them in Comments section, and we shall answer.

Vote for your favorite

Do you think we are right or mistaken in our choice? Vote by clicking "Like" button near your favorite graphics card.


NVIDIA Quadro RTX A6000
Quadro RTX A6000
AMD Radeon Instinct MI250
Radeon Instinct MI250

Comparisons with similar GPUs

We selected several comparisons of graphics cards with performance close to those reviewed, providing you with more options to consider.

Community ratings

Here you can see the user ratings of the compared graphics cards, as well as rate them yourself.


3.1 460 votes

Rate Quadro RTX A6000 on a scale of 1 to 5:

  • 1
  • 2
  • 3
  • 4
  • 5
3.3 18 votes

Rate Radeon Instinct MI250 on a scale of 1 to 5:

  • 1
  • 2
  • 3
  • 4
  • 5

Questions & comments

Here you can ask a question about this comparison, agree or disagree with our judgements, or report an error or mismatch.